Healthcare provider well-being is a growing area of professional concern due to its impact on both the clinician’s health and patient outcomes. Research suggests that well-being concerns, like burnout, begin in health professions education programs, during which students undergo rigorous academic and clinical training for future careers as clinicians. Drawing from a recent multi-institutional, multi-disciplinary study of health professions students, this presentation will discuss issues of well-being in health professions education, including its prevalence, common interventions, and the students’ perceptions and experiences with well-being and stress. The presentation will emphasize how program culture, academic coursework, and clinical experiences impact student stress and well-being, and discuss how faculty and administrators can authentically support their students during the program.